Carfentanil’s street price per dose is likely lower than that of heroin. Carfentanil is used to rapidly immobilize large animals in veterinary medicine and has no U.S. Deaths involving carfentanil, an analog reportedly 10,000 times more potent than morphine and 100 times more potent than fentanyl, were first reported in Florida, Michigan, and Ohio in 2016 and described in an August 2016 CDC Health Advisory ( 1, 5). This CDC Health Advisory has been updated twice to address increases in fentanyl and fentanyl analog overdoses and their co-occurrence with nonopioids ( 4). On October 26, 2015, CDC issued a Health Advisory regarding rapid increases in deaths involving fentanyl.
Increased prevalence of illicitly manufactured fentanyl and fentanyl analogs has contributed substantially to overdose deaths in the United States ( 1– 3).
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